The number of Th17 cells in the spleen and cardiac tissue is decreased by Ad-IL-17AR:Fc.
2013-08-20T01:41:39Z (GMT) by
<p>(<i>A</i>) Representative flow cytometry images of Th17 (CD4<sup>+</sup> IL-17<sup>+</sup>) cells from each group gated on CD4<sup>+</sup> T cells. Numbers in the upper right quadrants and lower right quadrants indicate the separate percentages of Th17 cells and CD4<sup>+</sup> T cells, respectively. PE = phycoerythrin; FITC = fluorescein isothiocyanate. (<i>B</i>) The percentage of Th17 (CD4<sup>+</sup> IL-17<sup>+</sup>) cells in each group was analyzed using CellQuest software. (<i>C</i>) The levels of IL-6 and TNF-α in the supernatants of heart homogenates detected using ELISA. The data represent the mean ± SEM for 6 mice per group. **<i>P</i><0.01 vs control group, *<i>p</i><0.05 vs control group.</p>