Figure_11.tif (1.21 MB)
The mRNA expressions of HO-1, NQO1, and GST-α1 in the brains in control group (n = 10), SAH group (n = 10), SAH+vehicle group (n = 10), and SAH+tBHQ group (n = 10).
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posted on 2014-05-21, 03:54 authored by Zhong Wang, Chengyuan Ji, Lingyun Wu, Jiaoxue Qiu, Qi Li, Zhong Shao, Gang ChenSAH was found to induce a marked increase in HO-1, NQO1, and GST-α1 mRNA expression in the rat SAH brains compared with control group. After tBHQ administration, the mRNA expressions of the downstream Keap1/Nrf2/ARE pathway related agents were significantly up-regulated relative to the SAH+vehicle group. ** P<0.01 and * P<0.05 vs. control group, ## P<0.01 and # P<0.05 vs. SAH+vehicle group, vs. P>0.05 vs. SAH group.
