The mRNA expressions of HO-1, NQO1, and GST-α1 in the brains in control group (n = 10), SAH group (n = 10), SAH+vehicle group (n = 10), and SAH+tBHQ group (n = 10).
2014-05-21T03:54:43Z (GMT) by
<p>SAH was found to induce a marked increase in HO-1, NQO1, and GST-α1 mRNA expression in the rat SAH brains compared with control group. After tBHQ administration, the mRNA expressions of the downstream Keap1/Nrf2/ARE pathway related agents were significantly up-regulated relative to the SAH+vehicle group. ** <i>P</i><0.01 and * <i>P</i><0.05 vs. control group, ## <i>P</i><0.01 and # <i>P</i><0.05 vs. SAH+vehicle group, vs. <i>P</i>>0.05 vs. SAH group.</p>