The localization of miR-21 in invasive cervical cancer tissues.

A and B: tissue sections from cervical cancer samples were incubated with DIG-labeled locked nuclei acid (LNA) probe to miR-21. Strong signals were observed in the stroma. The signal was also seen at the rim of cancer cells adjacent to the stroma (Bar: 100 μm). C: RNU6B staining in cervical cancer and stromal nuclei (Bar: 50 μm). D: cervical cancer negative control staining using a ‘scramble’ LNA probe (Bar: 50 μm).