Figure_7.tif (4.09 MB)
The crystal structure of T. brucei dihydrofolate reductase, TbDHFR (PDB 3qfx) [44].
figure
posted on 2012-07-24, 01:16 authored by William N. Setzer, Ifedayo V. OgungbeThe docked structure is 3-O-acetylkhayalactone (magenta). The co-crystallized ligand, pyrimethamine, is shown as a green wire figure and the NADPH cofactor as a space-filling structure.
