Fig_4.tif (380.43 kB)
The characteristics of stromal fibroblasts after treatment with culture media from HeLa cells (HeLa CM) and TGF-β1.
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posted on 2015-05-26, 15:16 authored by Sureewan Bumrungthai, Tipaya Ekalaksananan, Mark Francis Evans, Peechanika Chopjitt, Thumwadee Tangsiriwatthana, Natcha Patarapadungkit, Pilaiwan Kleebkaow, Sanguanchoke Luanratanakorn, Bunkerd Kongyingyoes, Suchin Worawichawong, Chamsai PientongThe level of transcriptional change was examined by real-time RT-PCR. A: the expression of miR-21 was significantly up-regulated at 24 and 48 h after HeLa CM or TGF-β1 treatment. B and C: the expression of IL-6 and alpha-SMA was significantly up-regulated at 48 h after HeLa CM or TGF-β1 treatment. D: PDCD4 was significantly down-regulated at 48 h after HeLa CM or TGF-β1 treatment. (*: significant differences from control at P<0.05)
