The <i>Rhox</i> cluster is classified into two regulated regions by DNA methylation.

<p>a) Overview of the DNA methylation profile of the <i>Rhox</i> cluster. b) The DNA methylation status of anterior and posterior <i>Rhox</i> genes. The left panel represents the MeDIP signal in each <i>Rhox</i> promoter. The right panel shows the quantitative estimation of DNA methylation by MALDI/TOFMAS. The arrowhead indicates the region of DNA analyzed for methylation. c) Expression profile of anterior and posterior <i>Rhox</i> genes.</p>

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