The FtsY from <i>Pyrococcus furiosus</i>.

<p>(A) Sequence alignment of FtsY/SRs of known structure including <i>Pfu</i>, <i>Thermus aquaticus (Taq)</i>, <i>Thermotoga maritima (Tma)</i>, <i>Mycoplasma mycoides (Mmyc)</i> and <i>Arabidopsis thaliana (Atha)</i> (chloroplast). The protease sensitive sites observed in <i>E.coli</i> and <i>Taq</i> FtsYs upon FtsY•Ffh complex formation are indicated (x). The ELEX<sub>2</sub>LX<sub>3</sub>D in the N domain is indicated. (B) Overall structure of the <i>apo</i> monomer of <i>Pfu</i>-FtsY. Two views related by a 180° rotation along a vertical axis are shown. The secondary structure elements of <i>Pfu</i>-FtsY are indicated. α-helices and conserved motifs of the SRP/SR-GTPases subfamily are labeled.</p>