The 9-gene C35/claudin-low signature is down-regulated in a subset of human breast cell lines.
Eight cell lines exhibit low expression of CDH1, CLDN7, CRB3, KRT8, TACSTD1, IRF6, SPINT2 and MAL2 when cultured on plastic. MARVELD3 could not be assessed due to particularly low levels of expression. Technical triplicate mRNA expression data is shown for each line. HMEC cDNA is shown for comparison.