TLR4 deficiency reduced macrophage accumulation in diabetic nephropathy.

<p>Macrophage (CD68<sup>+</sup> or F8/40<sup>+</sup>) accumulation was evident in WT mice with diabetes, but prevented by TLR4 deficiency in both the interstitial (A) and glomerular (B & C) compartments. Data are present as means ± SEM; * <i>p</i><0.05; *** <i>p</i><0.001.</p>