TIA-1<sup>+</sup> granules indicate stress in the intestinal mucosa in active CD.

<p>MICA/B cytoplasmic expression colocalized with TIA-1<sup>+</sup> granules. (A) MICA/B (red) and TIA-1 (green) in different cell populations in a severe enteropathy of a CD patient. Epithelium was delimited in the picture with a thin line (scan zoom 0.7, magnification 100×). (B) Enlarged picture of (A).</p>