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Summary of nuclear markers significantly associated/linked1 to growth traits and their annotations.

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posted on 2012-05-04, 00:54 authored by Mohamed Salem, Roger L. Vallejo, Timothy D. Leeds, Yniv Palti, Sixin Liu, Annas Sabbagh, Caird E. Rexroad III, Jianbo Yao
1

Body weight was recorded on each animal at approximately 7 (Weight2), 9 (Weight3) and 12 (Weight4) months post-hatching. A family-based sample that included 40 full-sib families each with 17 progeny were genotyped with 30 SNPs. Summary statistics were obtained with program PLINK version 1.07 [22].

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SNPs minor allele frequency (MAF).

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SNPs showing deviation from Hardy-Weinberg equilibrium. Exact P-value estimated using 20,000 permutations.

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QTDT population stratification test.

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t-statistic for regression of phenotype on allele count P is the asymptotic P-value for t-statistic, was estimated using 20,000 permutations.

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Genome-wide association analysis with family data (GWAF) R package [23].

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Family-based Measured Genotype and QTLD analysis was performed with software SOLAR version 4.0 [24] or QTDT quantitative trait disequilibrium test [21].

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Family-based Bayesian quantitative trait nucleotide (BQTN) analysis was performed with software SOLAR version 4.0 [24].

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SNP annotation; gene name and SNP location (ORF/5′UTR/3′UTR), SYN = Synonymous, NON-SYN = Non-synonymous.

NA indicates statistically insignificant estimate.

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