Structures of the investigated compounds from the first-generation and second-generation of MurD sulfonamide inhibitors.

<p>The MurD inhibitory activities and residual activities (RA) of these compounds were published previously <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052817#pone.0052817-Humljan1" target="_blank">[8]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052817#pone.0052817-Sosi1" target="_blank">[11]</a>. The first and the second generation sulfonamide inhibitors are marked in green and blue respectively.</p>