Structures of the 1∶2 complexes.

2012-03-08T00:06:38Z (GMT) by Xiaodong Pang Huan-Xiang Zhou
<p>(A) GH:(GHR)<sub>2</sub>. (B) EPO:(EPOR)<sub>2</sub>. (C) PRL:(PRLR)<sub>2</sub>. The cytokine (GH, EPO, or PRL) is in the middle in green; receptor 2 (R2) is on the left and receptor 1 (R1) is on the right. Each receptor ECD is composed of an N-terminal subdomain (N1 in purple and N2 in blue) and a C-terminal subdomain (C1 in orange and C2 in red).</p>