Fig_1.tif (464.72 kB)
Structure of Inaba OSP:rTTHc conjugate.
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posted on 2015-07-08, 02:54 authored by Md. Abu Sayeed, Meagan Kelly Bufano, Peng Xu, Grace Eckhoff, Richelle C. Charles, Mohammad Murshid Alam, Tania Sultana, Md. Rasheduzzaman Rashu, Amanda Berger, Geoffrey Gonzalez-Escobedo, Anjali Mandlik, Taufiqur Rahman Bhuiyan, Daniel T. Leung, Regina C. LaRocque, Jason B. Harris, Stephen B. Calderwood, Firdausi Qadri, W. F. Vann, Pavol Kováč, Edward T. RyanVariations of conjugates containing 3, 5, or 10 moles of OSP per mole carrier were developed. rTTHc = recombinant tetanus toxoid heavy chain fragment.
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molar loading ratioMemory B Celllpscholera conjugate vaccineTetanus Toxin Heavy Chainospcholerae O 1 Inabacholerae O 1 Inaba strain PIC 018Mice BackgroundVibrio choleraeconjugate vaccineIntestinal lamina proprial IgA responsesmemory B cell responsesmouse survival cholera challenge model.ConclusionWe report developmentintradermal vaccinationimmunization.Principle FindingsImmunized micesquaric acid chemistryLamina Proprial Responses
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