Structural comparison of VLRC with lamprey VLRA and VLRB.

VLRC is shown in magenta, whereas VLRA and VLRB are shown in green and their bound ligands in gray. (A) Superimposition of VLRC and the lamprey VLRB.RBC36 trisaccharide complex [19]. (B) Superimposition of VLRC and the lamprey VLRB.2D-HEL complex [20]. (C) Superimposition of VLRC and the lamprey VLRA.R2.1-HEL complex [22]. Arrows indicate protruding loops located in the LRRCT of VLRA and VLRB.