Sphere cells form tumors with histological features of parental ones.

<p>Light micrographs of tumors formed by subcutaneous injection of sphere cells into NOD-SCID mice (right panels), which are obtained by cultures of (A) unsorted HGC-1, (B) unsorted HGC-2 and (C) unsorted HGC-4 tumor cells. Histological features of tumors formed in mice correspond well with those of parental ones (left panels). Tissue specimens are stained with hematoxylin and eosin. Scale bars represent 50 µm.</p>