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Skin feeding versus membrane feeding.

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posted on 20.02.2013 by Teun Bousema, Rhoel R. Dinglasan, Isabelle Morlais, Louis C. Gouagna, Travis van Warmerdam, Parfait H. Awono-Ambene, Sarah Bonnet, Mouctar Diallo, Mamadou Coulibaly, Timoléon Tchuinkam, Bert Mulder, Geoff Targett, Chris Drakeley, Colin Sutherland, Vincent Robert, Ogobara Doumbo, Yeya Touré, Patricia M. Graves, Will Roeffen, Robert Sauerwein, Ashley Birkett, Emily Locke, Merribeth Morin, Yimin Wu, Thomas S. Churcher

Results are from 161 paired experiments plotted in a Bland-Altman plot. Points above the line had higher infectivity in the skin feeding assay than the whole blood SMFA. Point colour denotes the study using the same key as in Figure 2. The shape of the point denotes the country the experiment was carried out in, be it Cameroon (circle), Mali (triangle) or Senegal (diamond). The size of the points indicates the relative average number of mosquitoes dissected in the experiment, with points>50 mosquitoes dissected having the same size). In 117 experiments (72.7%), the proportion of infected mosquitoes was higher in skin feeding assays compared to the paired whole blood membrane feeding assay; in 43 experiments (26.7%) the opposite was observed.

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