Figure_5.tif (205.22 kB)
Silencing of CHOP by siRNA inhibited induction of DR5 upregulation by casticin and apoptosis by co-treatment with casticin and TRAIL in BGC-823 cells.
figure
posted on 2013-03-12, 09:02 authored by Yuan Zhou, Li Tian, Lingzhi Long, Meifang Quan, Fei Liu, Jianguo CaoEffects of siRNA for CHOP on the action of casticin-induced DR5 and CHOP expression (A and B) using western blot analysis and TRAIL-mediated apoptosis (C) in BGC-823 cells (mean±SD, n = 3). *P<0.05 vs. treatment with DMSO; #P<0.05 vs. treatment with 1 µmol/l casticin plus 50 ng/ml TRAIL in control and scRNA transfected cells.
