Setup and design of the Polyfermentor Intestinal Model (PolyFermS).

Control (CR) and test reactors (TR) were continuously inoculated with effluents from inoculum reactors (IR) containing 30% (v/v) of fecal beads from donors A (model A), B (model B) and C (model C), respectively. Metabolites were quantified daily by HPLC analysis. Community structure was studied by HITChip analyses at selected time points t1, t2, t3 and t4. RT, mean retention time.