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Secondary and tertiary formation depends on cell death.

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posted on 2010-07-01, 01:02 authored by David E. Larson, Ruth I. Johnson, Maciej Swat, Julia B. Cordero, James A. Glazier, Ross L. Cagan

(A) Image captured at 50,000 MCS from a simulation of reduced cell death (L = 12) showed numerous ectopic, end-to-end 2°-like cells (•) and vertices with three cells in the 3° locus (arrows). Asterisk labels an ommatidium enlarged in inset. (B) Graph showing the decrease in cell number over time for different levels of cell death. L controlled the ‘strength’ of cell death as described in Results. Cell death was initiated at 10,000 MCS and each line represents the result of a single representative simulation from at least two repetitions. (C) Graph showing formation of 2°s over time for different levels of cell death. Each line represents the result of a single representative simulation from at least two repetitions. (D) Graph showing formation of 3°s over time for different levels of cell death. Each line represents the result of a single representative simulation from at least two repetitions. (E) Graph showing number of both 2° and 3°s at 15,000 MCS as cell death parameters are changed to increase the total cell number. Each point represents a different cell death parameter in the simulations from (B), (C) and (D).

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