Schematics of breeding tubercle organization and regulation.

<p>(A) Schematic of cellular composition of breeding tubercles and regular epidermis. The different layers and cell types are colour-coded. On the right side, the sites of cellular structures and junctions shown in <a href="" target="_blank">Figure 3</a> (TEM) are indicated. (B) Model for the dual role of TAp63/p53 on keratinocyte proliferation and differentiation, and its connection to ΔNp63. For details, see text.</p>