Figure_9.tif (3.03 MB)
Schematics of breeding tubercle organization and regulation.
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posted on 2014-01-09, 03:13 authored by Boris Fischer, Manuel Metzger, Rebecca Richardson, Philipp Knyphausen, Thomas Ramezani, Rainer Franzen, Elmon Schmelzer, Wilhelm Bloch, Thomas J. Carney, Matthias Hammerschmidt(A) Schematic of cellular composition of breeding tubercles and regular epidermis. The different layers and cell types are colour-coded. On the right side, the sites of cellular structures and junctions shown in Figure 3 (TEM) are indicated. (B) Model for the dual role of TAp63/p53 on keratinocyte proliferation and differentiation, and its connection to ΔNp63. For details, see text.