Schematic structure of the hymenoptaecin precursors from different hymenopteran species:

<p>A) <i>Apis mellifera</i> (GenBank Acc. No.: NP_001011615) or <i>Bombus ignitus</i> (GenBank Acc. No.: ACA04900); B) <i>Nasonia vitripennis</i>: (GenBank Acc. No.: NP_001165829 XP_001607881); C) <i>Harpegnathos saltator</i> 1 (GenBank Acc. No.: EFN79831); D) <i>Harpegnathos saltator</i> 2 (GenBank Acc. No.: EFN79832); E) <i>Camponotus floridanus</i> (GenBank Acc. No.: HQ315784); F) <i>Acromyrmex echinatior</i> (hymenoptaecin multipeptide precursor deduced from genome draft). The various domains are marked as follows: signal-sequence (grey hatched box), pro-sequence (white hatched box), hymenoptaecin-like domain (HLD, light grey box), hymenoptaecin domains (HD 1–6, dark grey boxes), proline-rich AMP-like peptide (AMP 1–2, white dotted boxes). The hymenoptaecin domains are flanked by the putative processing sites EAEP (EANP for <i>Harpegnathos</i>) (white box) and RR (or RxxR) (black box).</p>