Schematic representation of the mnemonic model for the mammalian glucokinase.

2015-04-14T02:49:45Z (GMT) by Pedro Saa Lars K. Nielsen
<p>This model proposes a slow conformational transition from a low-affinity state (<i>E</i><sup><i>*</i></sup>) to a high-affinity state (<i>E</i>) that can be enhanced with increasing glucose concentration yielding the observed cooperative behaviour.</p>