Fig_1.tif (1.1 MB)
Schematic depicting synthesis of OPF/SMA hydrogels.
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posted on 2016-01-18, 15:33 authored by Carl T. Gustafson, Felix Boakye-Agyeman, Cassandra L. Brinkman, Joel M. Reid, Robin Patel, Zeljko Bajzer, Mahrokh Dadsetan, Michael J. YaszemskiOPF/SMA hydrogels synthesized as described. Idealized OPF chain represented in blue, SMA is depicted in red, crosslinked between OPF chains. Vancomycin shown as red stars within the hydrogel.
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research groupantibiotic therapystock vancomycindosing schedulesside effectsantimicrobial agentsantimicrobial activityvancomycin releaseopfantimicrobial compoundsPatient compliance6 hourscombat SSIVancomycin release kinetics500 μ g drugloading mechanismcopolymermg hydrogelbiocompatible hydrogel matrices24 hourswound antibiotic treatmentControlled Deliveryantibiotic delivery vehiclepatient recovery timeCharged Hydrogels Surgical site infectionrelease formulationssite infection
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