Resveratrol regulates the expression of genes implicated in osteogenesis and adipogenesis.

A). Representative gel images of gene expression examined by semi-quantitative RT-PCR on cells subjected to concurrent treatment of BM/resveratrol with OIM for 3 days (OIM 3D-CT) or 7 days (OIM 7D-CT), or cells pretreated with BM/resveratrol for 12 days followed by 3 days of OIM (12D PT-3D OIM) or 7 days of AIM (12D PT–7D AIM) exposure. Expression of internal control gene Hsp90 from the same batch of cDNA for each gene is shown in the bottom row. B). Expression of each gene in resveratrol treated cells was quantified relative to that in BM treated cells and normalized by the expression of housekeeping gene Hsp90. Data shown are the mean values of three repeats. Error bars represent standard deviation. Concentration unit: µM. *: p<0.05 vs. BM. **: p = 0.055 vs. BM.