Representative cases of a healthy highly myopic eye with enlarged lamina pores (A–E) and an eye with primary open angle glaucoma and lamina cribrosa (LC) defects (F–J).

(A) A lamina pore can be seen within the optic disc cup (red arrowhead) in the optic disc photograph. (B) Multiple hyporeflective dots and a large hyporeflective region (red arrowhead) can be interpreted as lamina pores in en face optic disc images at the level of the LC. (C) Humphrey 24-2 pattern deviation plots show no glaucomatous visual field defect. Volume image (D) and horizontal B-scan image (E) corresponding to the green dotted line in (A). Note that the lamina structure was not fully defective in the hyporeflective region. (F) The LC defect can be seen in the inferior border of the optic disc rim (red arrowhead). (G) A wedge shaped hyporeflective region (red arrowhead) is also apparent in the en face image. (H) Humphrey 24-2 pattern deviation plots showed a glaucomatous visual field defect. Volume image (I) and horizontal B scan image (J) corresponding to the green dotted arrow in (F). Note that the lamina structure was fully defective in the hyporeflective region.