Representative Immunoblot analysis of L2 and ACTB protein expression.

Upper panel depicts L2 expression. Lanes 1 and 2: HPV16 positive E2 disrupted/integrated CaCx case samples (D1 and D2); Lanes 3, 5, and 7: HPV16 positive E2 intact/episomal (episomal or concomitant) European variants (EV1, EV2, EV3, respectively); Lanes 4, 6, and 8: HPV16 positive E2 intact/episomal (episomal or concomitant) Asian American variants (AAV3, AAV2, AAV1, respectively). Lower panel depicts ACTB expression among all the samples analysed. Sample details are illustrated in Table 5.