Raman spectroscopy to evaluate cytotoxic changes in response to effects of tissue adhesive on the DNA.

<p>(A) Averaged Raman spectra of DNA (a: control, b: PACA, c: Dermabond®) and the spectral differences of control and treated DNA (d: control-PACA, e: control-Dermabond®, f: PACA-Dermabond®). (B) Relative intensities of the Raman peaks for control DNA and treated DNA with two tissue adhesive (PACA and Dermabond®). (C) PCR amplification of the 776 bp β-actin using same dose of DNA samples (Control, PACA and Dermabond®).</p>