Figure_3.tif (379.74 kB)
ROC analysis of pGSN and APACHE III.
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posted on 2013-02-21, 07:35 authored by Po-Shun Lee, Sanjay R. Patel, David C. Christiani, Ednan Bajwa, Thomas P. Stossel, Aaron B. WaxmanReceiver operating curves of pGSN levels (solid line) and APACHE III scores (dotted line) identifying 28-day mortality in septic patients are generated. Area under curve is 0.86 for pGSN (95% confidence interval of 0.68–1.05, p = 0.011), and 0.81 for APACHE III (95% confidence interval of 0.60–1.02, p = 0.03. A pGSN level cutoff of <113.6 mg/L yields a 66.7% sensitivity and 93.3% specificity with a likelihood ratio of 10.