RNA binding interaction of umUPF1.

A channel is formed in the umUPF1 molecule eliciting the interaction between RNA and the protein. The residues that form the channel are presented in blue. The RNA molecule appears in black sticks. At the bottom, the detail of this interaction is presented. The identity and position of the key amino acids of umUPF1 involved in the interaction with RNA are depicted. Some residues have been previously reported as necessary for the interaction, while some others are suggested from our observations. This umUPF1 model was constructed using the 2XZO structure as a template.