RLX G-quadruplex structure models presented by software Chimera [<b>41</b>].

<p>(A) Top view (B) side view. (The purple balls stand for potassium ions). The docked results of berberine with RLX G-quadruplex presented by software PMV <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031201#pone.0031201-Sanner1" target="_blank">[42]</a> (C) end stacking (D) groove binding. (Berberine was shown as stick model while the G-quadruplex as molecular surface model).</p>