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QBP1 interferes with Orb2-mediated memory consolidation in vivo.

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posted on 2016-01-28, 12:42 authored by Rubén Hervás, Liying Li, Amitabha Majumdar, María del Carmen Fernández-Ramírez, Jay R. Unruh, Brian D. Slaughter, Albert Galera-Prat, Elena Santana, Mari Suzuki, Yoshitaka Nagai, Marta Bruix, Sergio Casas-Tintó, Margarita Menéndez, Douglas V. Laurents, Kausik Si, Mariano Carrión-Vázquez

Pan-neuronal expression of QBP1 disrupts long-term male courtship suppression memory, while it does not interfere with short-term memory. Expression of QBP1 in the Δ80Q orb2 mutant background did not have any additive effect on long-term memory. The data are represented as the mean ± SEM. We assumed statistical significance at *p < 0.05 (One-way ANOVA). n = 16, 15, 25, 22, 18, 14, 15, 28, 27, 20 from left to right. The underlying data for panels in this figure can be found in S1 Data.

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