Proportions of CD4+ and CD8+ T cell subsets in splenotypes of vaccinated mice.

(A) CD4+ T cell subsets and CD8+ T cell subsets of all groups. (B) CD4+/CD8+ T cell ratios of experimental groups and PBS control group. Mouse groups were immunized as indicated in Fig 2. Error bars represent the SEM. *, P<0.05, **, P<0.01, ***, P<0.001; ns, no significant difference.