Profiles of HAV-specific IgA production in mucosal immune response to vaccination.

HAV IgA was detected by indirect ELISA in (A) vaginal secretions, (B) intestine, (C) respiratory tract and (D) stool homogenates of the mouse groups immunized as indicated in Fig 2. Each serum effective dose (presented as the GMT) is the reciprocal value of the maximum positive dilution. Error bars represent the SEM. *, P<0.05, **, P<0.01, ***, P<0.001; ns, no significant difference.