Pro-fibrotic effect of SR-uPA+/0 macrophages is limited to cardiac fibroblasts.
Fold increase in expression in Col1a1 mRNA in response to conditioned media from SR-uPA+/0 in comparison to NTG macrophages in A. isolated cardiac fibroblasts B. NIH-3T3 cells. Error bars represent S.D. N = 4–6 mice per genotype. C. Col1a1 expression (arbitrary C units normalized to Gapdh) in cardiac fibroblasts treated with conditioned media from SR-uPA+/0 macrophages treated with BEC or vehicle, N = 4 mice per treatment, error bars represent S.D.