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Prenatal metformin exposure alters glucose tolerance in the male offspring during HFD in adulthood.

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posted on 2013-02-15, 02:25 authored by Henriikka Salomäki, Laura H. Vähätalo, Kirsti Laurila, Norma T. Jäppinen, Anna-Maija Penttinen, Liisa Ailanen, Juan Ilyasizadeh, Ullamari Pesonen, Markku Koulu

Glucose tolerance was tested during RD (A, B) (age = 9–10 weeks) and after 5–6 weeks of a HFD intervention (age = 15–16 weeks) (C, D) (n = 12–19) Black circles (•) = prenatal control, white circles (○) = prenatal metformin. Data expressed as mean ± SEM. *P<0.05 by Bonferroni post hoc tests.

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