Figure_5.tif (3.3 MB)

Positive correlation between number of CD68-positive macrophages and sIL-2R levels.

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posted on 2013-11-13, 02:56 authored by Noriaki Yoshida, Miyo Oda, Yoshiaki Kuroda, Yuta Katayama, Yoshiko Okikawa, Taro Masunari, Megumu Fujiwara, Takashi Nishisaka, Naomi Sasaki, Yoshito Sadahira, Keichiro Mihara, Hideki Asaoku, Hirotaka Matsui, Masao Seto, Akiro Kimura, Koji Arihiro, Akira Sakai

We counted the number of CD68- or CD163-positive macrophages in DLBCL, FL and RLH. Representative images of CD68-positive or CD163-positive macrophages in DLBCL and FL are shown (A–D). We also analyzed the correlations between number of CD68-positive macrophages and sIL-2R levels in DLBCL, FL and RLH. Intrafollicular macrophages were counted in FL and RLH. In both DLBCL and FL, the number of CD 68-positive macrophages was higher than that in RLH. (E) In both DLBCL and FL, the number of CD163-positive macrophages was significantly higher than that in RLH. (F) There was a positive correlation between the number of CD68-positive macrophages and sIL-2R levels in FL (right, ρ = 0.5294, p-value = 0.0289) (G). There was also a positive correlation between the number of CD68-positive macrophages and sIL-2R concentrations in extranodal samples of DLBCL. (right, ρ = 0.5891, p-value = 0.0039) (H). *Significant correlations were observed.