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PfCelTOS-specific antibodies raised by protein immunization react with P. falciparum and P. berghei sporozoites.

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posted on 2010-08-19, 01:35 authored by Elke S Bergmann-Leitner, Ryan M. Mease, Patricia De La Vega, Tatyana Savranskaya, Mark Polhemus, Christian Ockenhouse, Evelina Angov

Reactivity of polyclonal anti-PfCelTOS antibodies against P. falciparum (Panel A) and P. berghei sporozoites (Panel B) and reactivity of PfCelTOS-specific mAb 2C7 against P. falciparum (Panel C) and P. berghei-specific mAb 15E2 (Panel D) against P. berghei sporozoites. The antisera used for the staining were from the post-3 sera ( =  prechallenge) and were tested at 1∶200 dilutions. Images were taken at 1,000x magnification.

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