Overexpression of Morgue results in lethality.
2013-09-30T01:56:29Z (GMT) by
<p>Effects of widespread Morgue expression on fly viability. Counts of heterozygote (balancer) and homozygote non-balancer (+) progeny derived from genetic crosses where P[<i>da</i>-Gal4] was used to drive expression of P[UAS-GFP] or P[UAS-Morgue]. Homozygous P[<i>da</i>-Gal4] or P[<i>da</i>-Gal4],P[UAS-GFP] flies are viable while P[<i>da</i>-Gal4],P[UAS-Morgue] homozygotes are completely lethal. Flies containing two copies of P[<i>da</i>-Gal4] and one copy of P[UAS-Morgue] or vice versa exhibit either complete or significant lethality. UAS-morgue1 and UAS-morgue2 represent independent insertions of P[UAS-Morgue].</p>