Number of dendrites per LC in epidermal sheets.

(A) Microscopic examination revealed each LC to have a distinct cell body from which dendrites protruded (bar = 10µm). Two individual LCs designated (i) and (ii) with 4 and 5 dendrites per cell, indicated by the white and red arrows, respectively. Percentage frequency of dendrites per LC in (B) pre-cultured epidermal sheets and post-cultured epidermal sheets at 24 (C) and 48 (D) hours; untreated skin (black bars), skin treated with H1 VLPs delivered by ID injection (white bars). Data presented as mean ± SEM (n = 8).