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Neutrophil (PMN) and monocyte infiltration is reduced in the lung of PF4-/- mice after mesenteric IR injury.

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posted on 2012-07-06, 01:01 authored by Peter H. Lapchak, Antonis Ioannou, Poonam Rani, Linda A. Lieberman, Kazuhisa Yoshiya, Lakshmi Kannan, Jurandir J. Dalle Lucca, M. Anna Kowalska, George C. Tsokos

Tissue sections of lung of B6 and PF4-/- mice after 30 minutes of mesenteric ischemia and 3 hrs of reperfusion and were stained for neutrophils (A-F, red) and monocytes (G-L, red) and counterstained with hematoxylin (blue). A total of 5–8 mice were used for each control and experimental groups in two experiments. (M) Neutrophil infiltration score, (N) Monocyte infiltration score. ns: not significant *p≤0.05 for IR compared to sham controls. Red: Positive Staining.

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