Nebula co-upregulation rescues synaptic bouton over-proliferation caused by APP.

(A) Images representing the neuromuscular junction of 3^rd instar larvae at segment A2 of muscle segment 6/7. HRP staining outlining synaptic boutons. Scale bar = 10 µm. (B) Quantification of the number of boutons normalized to the muscle surface area (MSA). (C) Magnified images demonstrating the presence of satellite bouton phenotype (arrowheads) in genotypes with APP upregulation. Scale bar = 5 µm. (D) Quantification of the percentage of boutons that are satellite. n≥6 experiments in (B) and (D). All values represent mean ± S.E.M, * p≤0.05 compared to control.