NanoATV within marginal zone macrophages of the spleen.

Confocal microscopy images of cryosectioned spleen collected 12 h after intraperitoneal injection of nanoATV. Immunofluorescence images are as follows: (A) Cell nuclei stained with DAPI (blue); (B) Macrophages stained with CD169 and Alexa Fluor 488 (green); (C) NanoATV labeled with CF633 (pink); (D) Overlay of CD169-labeled macrophages and CF633-labeled nanoATV. Images were acquired with a LSM 710 confocal microscopy at 10x. (scale bars = 100 μm).