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NPS enhances subthreshold membrane potential oscillations in LA projection neurons.

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posted on 2011-03-18, 00:15 authored by Susanne Meis, Oliver Stork, Thomas Munsch

(A, B) Examples of subthreshold oscillations in a LA projection neuron before (A) and during (B) action of NPS. (C) Corresponding FFT analysis illustrate predominant theta frequencies enhanced by NPS. (D) Peak amplitude as well as frequency are significantly enlarged by addition of NPS. (E, F) Examples of subthreshold oscillations in a LA projection neuron before (E) and during (F) action of NPS in the presence of AP-5 and DNQX to block glutamatergic transmission. (G) Corresponding FFT analysis illustrate block of NPS effect. (H) Peak amplitude as well as frequency are unchanged by NPS * P<0.05, ** P<0.01.

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