Mutants with altered ovulation dynamics recover from heat stress differently than the wild type.

2014-08-28T03:17:12Z (GMT) by Erin Z. Aprison Ilya Ruvinsky
<p>(A) Schematic depiction of several key components of Ca<sup>2+</sup> signaling that regulates ovulation. Modified from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0105513#pone.0105513-Allman1" target="_blank">[53]</a>. (B) Recovery of fecundity (after a 24-hour heat stress at 31°C) in a mutant with up-regulated Ca<sup>2+</sup> signaling is lower than in a wild type control (binomial test <i>p</i> = 4.3×10<sup>−9</sup>). (C) Recovery of fecundity (after a 24-hour heat stress at 29°C) of mutants or chemical treatment that down-regulate Ca<sup>2+</sup> signaling is higher than in a wild type control: <i>itr-1</i> (binomial test <i>p</i> = 7.7×10<sup>−28</sup>), <i>crt-1</i> (<i>p</i> = 2×10<sup>−25</sup>), and dantrolene (<i>p</i> = 1.6×10<sup>−8</sup>). Error bars are s.d.</p>