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Multilayer and co-deposition experiments with pharmaceutical substances.

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posted on 2013-02-20, 01:31 authored by Eman S. Zarie, Viktor Kaidas, Dawit Gedamu, Yogendra K. Mishra, Rainer Adelung, Franz H. Furkert, Regina Scherließ, Hartwig Steckel, Birte Groessner-Schreiber

a) Comparative dissolution profile of Metronidazole alone and Metronidazole covered with the PLGA thin layer. The insets (i) and (ii) in the fig. 4a show the schematic of the multilayer coating and SEM image of the TE deposited Metronidazole drug respectively. b) 3D SEM micrograph an a cross section cut in the structure of a double layer showing top layer of Tetracaine and second layer of Metronidazole deposited on Ti substrate, c) SEM Image of the nanocomposite of Tetracaine-HCl with Ag on the Si substrate fabricated by co-deposition from two sources simultaneously sources and d) SEM image of Tetracaine-HCl without silver for comparison.

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