Molecular modeling analysis.

<p>(<b>A</b>) Molecular modeling of T305Y mutant (pink) and Akt <i>O</i>-GlcNAcylated at Thr 305 (green). Tyr305, <i>O</i>-GlcNAcylated Thr305 and Asp325 are represented as sticks. (<b>B</b>) Molecular modeling of T312Y mutant (pink) and Akt <i>O</i>-GlcNAcylated at Thr 312 (green). Tyr312, <i>O</i>-GlcNAcylated Thr312, Asp274 and Lys276 are shown as sticks. Additionally, oxygen atoms are shown in red, nitrogen atoms are shown in blue, and the hydrogen bonds are shown in red dot lines.</p>