Figure_8.tif (1.51 MB)
Micro-injection of BH3 peptides induces mitochondrial fragmentation of Bax−/−/Bak−/− MEFs.
figure
posted on 2009-05-21, 02:19 authored by Emelyn H. Shroff, Colleen M. Snyder, G. R. Scott Budinger, Manu Jain, Teng-Leong Chew, Satya Khuon, Harris Perlman, Navdeep S. Chandel(A and B) Mitochondria of Bax−/−/Bak−/− MEFs were stained with Mitotracker Red CMXRos (50 nM) followed by microinjection of 100 µM BID (A) or mutant BID peptide (B) that does not contain 8D-arginines. Injected cells were tracked by dextran FITC.
