Figure_1.tif (304.63 kB)
Manhattan plot and Q-Q plot of genome-wide meta-analysis.
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posted on 2013-11-07, 03:26 authored by Peng Chen, Rick Twee-Hee Ong, Wan-Ting Tay, Xueling Sim, Mohammad Ali, Haiyan Xu, Chen Suo, Jianjun Liu, Kee-Seng Chia, Eranga Vithana, Terri L. Young, Tin Aung, Wei-Yen Lim, Chiea-Chuen Khor, Ching-Yu Cheng, Tien-Yin Wong, Yik-Ying Teo, E-Shyong Tai(A) The Manhattan plot of the meta-analysis of Chinese, Malays and Indians. The minus log10 of P-values (Y-axis) of inverse-variance meta-analysis across the 22 autosomal chromosomes after genomic control were plotted against the genomic coordinates. The horizontal line represents the genome-wide significant level of 5x10-8. (B) Q-Q plot of the observed P-values (Y-axis) against the expected P-values (X-axis). The diagonal line and its 95% confidence envelop were also plotted.
