Figure_5.tif (147.07 kB)
MDT-15 is required for defense against P. aeruginosa infection.
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posted on 2014-05-29, 04:26 authored by Read Pukkila-Worley, Rhonda L. Feinbaum, Deborah L. McEwan, Annie L. Conery, Frederick M. AusubelA P. aeruginosa pathogenesis assay with wild-type N2, mdt-15(tm2182) mutant worms and mdt-15(tm2182) animals carrying pmdt-15::mdt-15 (three independent lines agEx116, agEx117 and agEx118) is shown. The difference in P. aeruginosa susceptibility between mdt-15(tm2182) animals and each of the three transgenic lines carrying pmdt-15::mdt-15 is significant, as is the survival difference between N2 and mdt-15(tm2182) animals (p<0.001). For sample sizes, see Table S3.
